Paper Details

Paper Code :  20180321

Paper Title   :  Role of protein Z and protein C in neonates with respiratory distress syndrome in Egypt (experience of one centre)

Journal Title   :  Pakistan Journal of Biological Sciences


Pak J Biol Sci. 2009 Nov 15;12(22):1468-73.


The aim of this study is to evaluate Protein Z (PTZ) and protein C (PTC) levels in newborns suffering from RDS, healthy preterm and full term newborns and to compare PTZ serum levels in RDS preterm infants with healthy preterm before and after recovery. Sixty newborn infants, recruited from the neonatal unit, were enrolled in the study and divided into 3 groups: Group (I): 20 preterm with RDS, Group (II): 20 healthy preterm control newborns (CPT) and Group (III): 20 healthy full term control newborns (CFT). Protein Z and C were measured using ELISA kits. The results of the study showed lower levels of protein Z were obtained in RDS group compared to preterm controls whose levels were significantly lower than in full-term controls. A significant increase in PTZ levels in RDS' group after recovery, when compared to preterm controls. In RDS, no significant correlations existed between PTZ levels (before and after recovery) and routine investigations except for a significant negative correlation with platelets count. No significant differences were found in PTC levels between the 3 studied groups. To conclude: premature newborns suffering from RDS showed decreased serum protein Z levels than normal preterm control newborns with further increase in its pattern after recovery. Further studies are recommended to evaluate the role of PTZ on outcome in premature newborns with RDS and to evaluate the relationship between protein PTZ and PTC and other coagulation factors incriminated in the development of RDS.



Please Be Advised

:: Ordering full-text copy of this paper is available.


Available Formats

:: Electronic copy (PDF) format.


Turnaround Time

:: Regular (within 24 to 72 hours) no additional charge.

:: Rush (within 8 to 12 working hours) 10 L.E.


Delivery Options

:: By E-mail (according to the size).



:: Click on Request this Paper Link in the Gray bar on this page.

:: A message with the final cost will deliver to your E-mail / Mobile.


Payment Options

:: Instant Money Transfer from any Egyptian's Post Office.

:: Bank Transfer Order to our Accounts Egypt / Saudi Arabia.

:: Deposit option (Minimum 50 L.E.).

Sign Up

Selected Papers

Published On Egypt


"EgyDoctor.Net gives me access to the right information in a timely fashion and supporting me in both of my M.Sc. and PH.D. in an efficient and economical way.

A. Hosni Ph.D., MRCS