Paper Details

Paper Code :  20048110

Paper Title   :  The use of rhBMP-2 for the treatment of congenital pseudarthrosis of the tibia: a case series

Journal Title   :  The Journal of bone and joint surgery. American volume


J Bone Joint Surg Am. 2010 Jan;92(1):177-85.

Richards BS, Oetgen ME, Johnston CE.

Congenital pseudarthrosis of the tibia is a rare disorder that is difficult to treat successfully. Despite varied initial clinical presentations, this condition results in a pathologic fracture in nearly all cases. Frequently, there is an accompanying fracture of the fibula. Both fractures are recalcitrant to standard treatment, and patients with this condition often require multiple surgical procedures in an effort to achieve fracture union and a functional extremity. Historically, many patients eventually have had painful low-functioning limbs or even amputation.



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